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Diabetes and the Kidney:
Diabetic Nephropathy

June 26 - 29, 2008 - Dublin, Ireland
 
   

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Time Thursday, 26 June
16.00 - 16.15 Welcome Address
Hermann Haller, Germany
Eberhard Ritz, Germany
16.15 - 17.15

Opening Plenary Lecture
Chairs: Hermann Haller, Germany
              Eberhard Ritz, Germany

  • Candidate Genes of Diabetic Nephropathy Identified by a Large Scale Association Study
    Shiro Maeda, Japan

  • Genetics of Diabetic Nephropathy – Does it Exist?
    Per-Henrik Groop, Finland
17.15 - 18.30 Opening Reception

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Time Friday, 27 June
08.30 - 09.30

Plenary Lecture
Chair: Dick de Zeeuw, The Netherlands

  • Epidemiology of Early Diabetic Nephropathy: Which is more important, Microalbuminuria or Early Progressive Renal Function Decline?
    Andrzej S. Krolewski, USA

  • Diabetes in Asia
    Juliana Chan, Hong Kon
09.30 - 10.00 Coffee & Networking Break
10.00 - 12.00 Translational Sessions 1

Hemodynamics and Hyperfiltration
Chair: Enyu Imai, Japan

  • Renal Circulatory Dynamics in Experimental Diabetes
    Gerald DiBona, USA

  • Obesity, Hypertension and Renal Hemodynamics
    John E. Hall, USA

  • Hyperfiltration - What is the Clinical Significance?
    George Jerums, Australia

  • Mechanical Stress in Diabetic Nephropathy: Implications for Vascular Integrity
    Luigi Gnudi, UK
12:00 - 12:15 Session Break
12:15 - 13:15 Industry Symposium
13.15 - 13.45 Lunch & Networking Break
13.45 - 14.30 Poster Session & Discussion
14.30 - 16.00 Translational Sessions 2

Controversies: Proteinuria and the Glomerular Barrier
Chair: Ton J. Rabelink, The Netherlands

  • The Role of the Endothelium
    Börje Haraldsson, Sweden

  • Communication Across the Basement Membrane
    Susan Quaggin, Canada

  • The Role of the Slit Diaphragm
    Thomas Benzing, Germany
16.00 - 16.30 Coffee & Networking Break
16.30 - 18:00 Translational Sessions 3

Proteinuria
Chair: Giancarlo Viberti, London, UK

  • The Dominant Role of the Proximal Tubular Cell in Governing Albuminuria
    Wayne D. Comper, USA

  • How does Proteinuria Cause Progressive Renal Damage?
    Giuseppe Remuzzi, Italy

  • Proteomics in Diabetes
    Visith Thongboonkerd, Thailand

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Time Saturday, 28 June
08.30 - 09.30

Plenary Lecture
Chair: Toshio Miyata, Japan

  • Albuminuria, a separate treatment target in diabetes?
    Dick de Zeeuw, The Netherlands

  • Growth Factors in Diabetic Nephropathy
    Fuad N. Ziyadeh, Lebanon
09.30 - 10.00 Coffee & Networking Break
10.00 - 12.00 Clinical Sessions

Prevention and Treatment
Chair: Karin Jandeleit-Dahm, Australia

  • Which Blood Pressure is Important in Diabetic Nephropathy?
    Eberhard Ritz, Germany

  • Does ROS Inhibition Help?
    Mark E. Cooper, Australia

  • Multifactorial Intervention: Should we Control Everything?
    Peter Rossing, Denmark

  • Antifibrotic Treatment Strategies
    Raghu Kalluri, USA
12.00 - 12.15 Session Break
12.15 - 13.15 Industry Symposium
13.15 - 13.45 Lunch & Networking Break
13.45 - 14.30 Poster Session & Discussion
14.30 - 16.00 Translational Sessions 4

New Treatment Strategies 1
Chair: Eberhard Ritz, Germany

  • AGE Inhibition
    Merlin C. Thomas, Australia

  • PKC Inhibition
    Hermann Haller, Germany

  • Glycosaminoglycan Based Drugs
    Johan van der Vlag, The Netherlands
16.00 - 16.30 Coffee & Networking Break
16.30 -18.00 Translational Sessions 5

New Treatment Strategies 2
Chair: Raghu Kalluri, USA

  • Novel Therapeutic Targets: HIF and PAI-1
    Toshio Miyata, Japan

  • Endothelin Blockade
    Jennifer S. Pollock, USA

  • Pro and Cons of VEGF Blockade in Diabetic Nephropathy
    Richard E. Johnson, USA

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Time Sunday, 29 June
09.00 - 10.00

Plenary Lecture
Chair: Dick de Zeeuw, The Netherlands (TBC)

  • Stem Cells and Diabetes
    Ton J. Rabelink, Netherlands

  • Altered Nephrogenesis Due to Maternal Diabetes
    Martine Lelièvre-Pégorier, France
10.00 - 10.30 Coffee & Networking Break
10.30 - 12.00 Basic Science Sessions
Clinical Sessions

Animal Models of Diabetic Nephropathy
Chair: Richard Johnson, USA

  • What is the Best Type I and II Mouse Model?
    Agnes Fogo, USA


  • Modeling Human Diabetic Nephropathy in Mice
    Matthew D. Breyer, USA

  • Phenotypic Analysis
    Kumar Sharma, USA

  • The Intrarenal RAS System: Lessons from Genetic Modified Mice. An Update
    Thomas M. Coffman, USA

Transplantation and Diabetic Nephropathy
Chair: Hermann Haller, Germany

  • Long-Term Effects of Pancreas Transplantation on Diabetic Nephropathy
    Paola Fioretto, Italy

  • Post-Transplant Diabetic Nephropathy
    Bertram Kasiske, USA

  • Epigenetics
    Assam El-Osta, Australia

  • EPO in Diabetic Nephropathy
    Jan Menne, Germany
12.00 - 13.00 Lunch & Networking Break
13.00 - 15.00 Translational Sessions 6

Interstitial and Tubular Disease
Chair: Fuad N. Ziyadeh, Lebanon

  • Structural and Functional Considerations of Interstitial and Tubular Injury in Type 1 Diabetes
    Michael Mauer, USA

  • Macrophages and Inflammation
    Catherine Goodson, Ireland

  • Regulation of Fibrosis
    Michael Zeisberg, USA

  • Inflammation Mechanisms in Diabetes
    Juan F. Navarro, Spain
15:00 -15.30

Plenary Lecture

  • Unmet Needs - What did we Learn and Where do we Go from Here?
    Eberhard Ritz, Germany
    Hermann Haller, Germany

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